 Genetic Equilibrium Theory & Application
The Hardy-Weinberg Model of genetic equilibrium describes a theoretical situation in which there is no change in the gene pool. At equilibrium there can be no change or evolution.
Consider a population whose gene pool contains the alleles for "B" and "b".
Assign the letter "p" to the frequency of the dominant allele "B" and the letter "q" to the frequency of the recessive allele "b".
We know that the sum of the alleles must equal 100% so:
p + q = 100% or p + q = 1
And all the random possible combinations of the members of a population would equal:
p2 + 2pq + q2
p = frequency of the dominant allele in the population
q = frequency of the recessive allele in a population
p2 = percentage of homozygous dominant individuals
q2 = percentage of heterozygous recessive individuals
2pq = percentage of heterozygous individuals
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